CBD Science: What Research has Revealed About Cannabidiol and Health

CBD Science: What Research has Revealed About Cannabidiol and Health

It’s tempting to think of cannabidiol (CBD), a non-psychoactive compound in cannabis, as an herbal panacea. After all, it’s being touted as a potential treatment for asthma, obesity, drug addiction, acne, Alzheimer’s, migraines, PTSD and insomnia, just to name a few conditions.

But research into CBD’s healthful properties has largely been stifled in the United States, until recently. So, much of the evidence is either historical (“Napoleon’s troops probably used it!”), anecdotal (“My aunt swears by it!”) or based on lab studies of animals (the rat was unavailable for comment).

However, times are changing. The June 2018 decision by the U.S. Food and Drug Administration to approve a cannabis-derived CBD drug called Epidiolex for treating certain forms of epilepsy is a positive sign that barriers to cannabis research could soon be a thing of the past. When you consider 30 states plus the District of Columbia have approved some form of medical cannabis, the need for answers and more CBD research is obvious.

We do know that cannabidiol is a key chemical messenger in the body’s endocannabinoid system, which is responsible for maintaining homeostasis and other functions from head to toe. (And there are claims CBD topicals can help with dandruff, athlete’s foot and everything in between).

There is a growing body of CBD research exploring the anti-inflammatory, anti-anxiety, anti-cancer, anti-you-name-it properties of cannabidiol. There are few definitive results yet. But urgent health needs, plus hundreds of CBD products trying to answer them, have a way of putting public demand ahead of the research curve.

How might it help you? Here are just a few of the applications that show promise.

CBD and convulsive disorders: The medical journal Epilepsia notes that cannabis has been used to treat epilepsy for centuries. Even as research continues, patients are using CBD to limit or eliminate seizures—as seen in numerous reports, most famously CNN’s docu-series Weed.

CBD and cancer: Some of the strongest support for medical applications of cannabis comes from cancer research, as reported by The National Academies of Sciences, Engineering and Medicine in its sweeping 2017 review of 10,000 scientific abstracts. Cannabinoids are helping cancer patients deal with pain, general wasting and the nausea and vomiting that come with chemotherapy, according to the British Journal of Clinical Pharmacology. Studies suggest CBD and other cannabinoids may also play a role in limiting tumor growth.

CBD and acne: A study in The Journal of Clinical Investigation cites its effectiveness in corralling over productive sebaceous (oil) glands, and limiting the inflammation that causes “acne vulgaris.”

CBD and anxiety: In a research review published in the journal Neurotherapeutics, researchers said there is “considerable potential” for CBD as a balm for a wide range of anxiety disorders, including post-traumatic stress disorder (PTSD), obsessive-compulsive behaviors and panic disorders.

CBD and addiction: Another Neurotherapeutics study makes the case for using CBD to limit “drug-seeking behaviors,” which is ironic, given how many times cannabis has been cited as a gateway to more dangerous drugs.  Now, it’s being seriously considered as an “exit drug.”

CBD and smoking cessation: An Addictive Behavior study showed that tapping a CBD inhaler decreased the number of cigarettes users smoked by 40 percent.

CBD and pain: The Journal of Experimental Medicine reported that CBD therapy soothed both chronic inflammatory and neurophathic (nerve) pain. It’s important to note it was a rat study. But rats have feelings, too.

One cannabinoid quirk: Often the effects of cannabis are enhanced by what is known as the entourage effect—combining, say, CBD with THC and terpenes, the volatile organic compounds that give cannabis its distinctive fragrance. If you want the whole effect, you may need the whole plant.

Based on current and future findings, there may be a wave of CBD-related therapies coming soon … or even this afternoon, depending on the advice you get at a dispensary. Given the limits of current science, you’ll have to be your own research scientist and lab rat. But it beats waiting for the next issue of Neurotherapeutics to hit your mailbox.

Image source: Gotgot44 / Wikimedia Commons

Why Is the World’s Top-Selling Cannabis Concentrates Brand Getting Into the CBD Market? Let Us Tell You

Why Is the World’s Top-Selling Cannabis Concentrates Brand Getting Into the CBD Market? Let Us Tell You

Why would an industry-leading cannabis brand known for its pure, potent THC concentrate products decide to branch into the CBD market?

Frankly, although we’ve spent five years building our THC product line, it wasn’t a difficult decision to bring The Clear into the cannabidiol (CBD) marketplace.

The Clear™ already holds a significant percentage of the vape cartridge category in the lucrative cannabis concentrates industry. But CBD products give us even more options and flexibility, and that’s what is fueling our expansion into America’s robust CBD market.

First, clinical data on the positive effects of CBD on various medical conditions continues to roll in. In December, the World Health Organization issued an important report that stated CBD is not harmful, has health benefits and does not have abuse potential, among other findings. While there have been years of anecdotal evidence, finally having scientific studies to point to is a critical component for helping educate people as to the effectiveness of CBD.

Second, the U.S. Food and Drug Administration (FDA) is beginning to open the door to cannabidiol products, with an advisory panel in April unanimously voting in favor of approving GW Pharma’s cannabis-derived CBD medication Epidiolex for treatment of certain forms of epilepsy

Third, more and more states are legalizing cannabis in various forms, and low-THC or CBD-only laws have been enacted in at least 15 states, according to the National Conference of State Legislatures. The Senate, meanwhile, has fast-tracked Sen. Mitch McConnell’s bill that would nationally legalize hemp, which would vastly improve the domestic economics of hemp-derived CBD. Awareness of CBD products and their benefits will only continue to grow as more people encounter legalized medical marijuana, medical hemp and patients using these products.

While modern cannabis is consumed in a number of different ways, including edibles and tinctures, non-smokable cannabis products are a key component of state medical marijuana laws in places like Minnesota, Texas, Florida and New York.

And vaporized CBD fits the bill nicely.

While we are encouraged by the 29 states that allow medical marijuana and the nine that have legalized adult-use cannabis, we believe consumers in every state should have access to potent, pure cannabis extracts now. To ensure this, we extract our CBD from US-grown hemp that is certified compliant with the 2014 Farm Bill.

And because the terpenes that give our products flavors like Orange Creme and Potent Pineapple are not cannabis-derived, we can send products that incorporate them in most states and many countries.

We believe The Clear will become a CBD market leader, just as it has been in state-regulated THC marketplaces. Initial sales figures in our CBD product test markets—Arizona, Colorado and California—already tell us that our move to CBD is the right one. In Colorado and California, which have been big markets for our THC products, we exceeded our THC sales in just a matter of months. And that was without marketing, simply making the CBD products available. As we start to market these products, the potential for our CBD products is huge.

Conversely, as the volume of CBD sales rises, it will augment the THC side of our business by boosting brand awareness. When consumers become familiar with the superior technology and unique flavors of our CBD products, they can easily move over to our THC offerings sold in state-regulated dispensaries. It’s a force multiplier for our business.

And beyond those regulated dispensaries, there is powerful potential in distribution to unregulated vendors where CBD products are currently sold: pharmacies, smoke shops, retail health-and-wellness businesses, spas, drug stores and more. And the cannabis product trend is not just domestic—our partners are planning to bring our products to Europe and Japan, and then to other markets in Asia.

Consumers are also hungry for science-based, lab-tested CBD products that will provide positive experiences for those who have not found success with inconsistent off-the-shelf CBD products. Reliability, efficacy and quality are key for consumers, and with products like The Clear™, consumers know how much CBD they are consuming with each puff of the vaporizer.

From providing relief for those suffering from chronic pain or terminal illnesses, to killing a craving for nicotine, there are so many potential benefits, applications and avenues for CBD products. In the coming years as companies like The Clear™ continue to expand cannabinoid research and develop new methodologies for producing cannabis extracts, and as more states support a wider variety of CBD products, we believe the CBD market has limitless potential—and we are honored to bring a better CBD product to the market for these customers and patients.

The Clear + Cannabidiol: Introducing the CBD Concentrate You’ve Been Waiting For

The Clear + Cannabidiol: Introducing the CBD Concentrate You’ve Been Waiting For

Some big news for consumers looking for a clean way to vape CBD: The Clear now offers a cannabidiol-specific line of vape pens that are available in all CBD-permitted states and beyond (see below).

We are thrilled to introduce: The Clear CBD.

As the producer of The Clear, America’s best-selling THC concentrate, we are known for our patented science, advanced technology and unparalleled design—as well as the efficacy and quality of our products. The Clear is now bringing that singular familiarity with cannabis concentrates to the non-psychoactive space, in both 420-legal markets and non.

Vaporizable cannabis is our passion and focus, and our mission is to make sure everyone has access to pure, potent cannabis extracts. So making our clean technology available to those who want to benefit from CBD without getting high is the logical next step in carrying out that important mission.

There are so many nuances that go into an effective, enjoyable and safe vaping experience—so you want to go with experts who stand behind the history of their product. In the last five years, The Clear has set the standard for excellence and exploration in the industry with our golden, potent and pure cannabis oil that is available in cartridges, syringes and honey buckets.

When we develop a new product, we make sure it is the best on market, and our vaporizer cartridges are a prime example. Our precision-made CBD cartridges will be familiar to anyone who has tried any of our popular THC products, as it’s important to us that all products bearing The Clear’s iconic badge utilize industry-leading hardware and technology.

We also know that consistency is everything in the cannabis space, whether we’re talking psychoactive or non-psychoactive products. So not only will our customers know exactly how much CBD is in each cartridge—but they will also know that every complete hit on a Clear CBD cartridge will draw exactly 10mg of CBD, every time.

As we tell our customers: “Know what’s in your cart(ridge).” By reaching for The Clear, you never have to worry. Our proven scientific processes make The Clear CBD as clean, pure and consistent as our THC products. We use state-of-the-art equipment for all of our processing. Our labs create the purest CBD concentrate isolate out there, testing at 99.9% CBD. And we are proud to use only United States-grown hemp.

The first six palate-pleasing flavors for our CBD cartridges are Grapevine, Strawberry, Blueberry, Lemon Lime, Orange Creme and Potent Pineapple. All of our flavors are made in-house with steam-distilled, naturally derived plant terpenes.

After very successful test runs in Arizona, Colorado and California, our global partners will soon expand availability to other North American locations, plus Europe and Japan—and then other markets in Asia and beyond.

There are seemingly countless CBD-centric companies out there on the market, but The Clear has a longstanding history and unparalleled experience with this medicinal plant, and we have the loyal customer base to prove it.

The Clear is here to stay, and we’ll continue to bring new, top-quality products—like The Clear CBD—to cannabis consumers for decades to come.